Luria finally met Max Delbrück at the annual meeting of the American Physical Society in December 1940. They spent New Year's Day in Luria's lab, playing with bacteriophage and planning experiments to do the next summer at Cold Spring Harbor Laboratory on Long Island. That summer the two did their first investigations into how phage multiply within bacteria, and discovered that different phage strains interfere with each other when attacking bacteria. At the end of 1941, Luria worked with biophysicist Thomas Anderson to take some of the first electron microscope pictures of bacteriophage and accurately measure their size. This work helped win him a Guggenheim fellowship, which allowed him to spend much of 1942 at Vanderbilt University with Delbrück. In 1943 he took an instructorship at Indiana University; soon afterward he did one his most important studies, demonstrating that bacteria mutated spontaneously into phage-resistant forms. Again in collaboration with Delbrück, Luria developed the 'fluctuation test' for calculating bacterial mutation rates. This work provided statistical evidence for the existence of genes in bacteria, and thus established microbes as suitable subjects for genetics research.
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Seeking the Secret of Life:
The DNA Story in New York
Bibliography
Further readingabout the history of molecular biology and science, and the science of DNA.
Biography / Forensics / Genetic Engineering / Genetics and Ethics / History / Human Genome / rDNA / Science
Allen, Garland E.
Thomas Hunt Morgan : the man and his science
Princeton, N.J. : Princeton University Press, c1978
Morgan, Thomas Hunt (Unites States)
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Shine, Ian. and Sylvia Wrobel
Thomas Hunt Morgan : pioneer of genetics / foreword by George W. Beadle.
Lexington : University Press of Kentucky, c1976
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Ithaca : Cornell University Press, 1981
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Comfort, Nathaniel C.
The tangled field : Barbara McClintock's search for the patterns of genetic control
Cambridge, Mass. : Harvard University Press, 2001
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Crick, Francis
What mad pursuit : a personal view of scientific discovery
New York: Basic Books, c1988
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Dubos, René J.
The professor, the institute, and DNA
New York: Rockefeller University Press, 1976
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Fischer, Ernst Peter
Thinking about science : Max Delbrück and the origins of molecular biology
New York : Norton, c1988
Delbrück, Max (United States)
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Gillham, Nicholas W.
A life of Sir Francis Galton: from African exploration to the birth of eugenics
New York, N.Y.: Oxford University Press, 2001
Galton, Francis, Sir (England)
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Henig, Robin Marantz
The monk in the garden: the lost and found genius of Gregor Mendel, the father of genetics
Boston: Houghton Mifflin, 2000
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Toward the habit of truth : a life in science
New York: Norton, c1990
Hoagland, Mahlon B. (United States)
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The statue within: an autobiography
New York : Basic Books, 1988
Jacob, François, 1920-
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For the love of enzymes : the odyssey of a biochemist
Cambridge, Mass. : Harvard University Press, 1989
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Luria, S. E.
A slot machine, a broken test tube : an autobiography
New York : Harper & Row, c1984
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Maddox, Brenda
Rosalind Franklin : the dark lady of DNA
New York : HarperCollins, 2002
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McCarty, Maclyn
The transforming principle : discovering that genes are made of DNA
New York: W.W. Norton, c1985
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Watson and DNA : making a scientific revolution
Cambridge, Mass.: Perseus Pub., 2003
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Dancing naked in the mind field
New York : Pantheon Books, c1998
Mullis, Kary B (United States)
Sciences - Biography
Stahl, Franklin W., editor.
We Can Sleep Later: Alfred D. Hershey and the Origins of Molecular Biology.
Cold Spring Harbor: Cold Spring Harbor Laboratory Press., 2000.
Hershey, Alfred D (United States).
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Watson, James D.
Genes, girls, and Gamow
New York : Oxford University Press, c2001
Watson, James D.
Molecular biologists – Biography
Watson, James D.; edited by Gunther S. Stent.
The double helix: a personal account of the discovery of the structure of DNA
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NOTE: First published in 1968
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Actual innocence : when justice goes wrong and how to make it right
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The DNA story: a documentary history of gene cloning
San Francisco: W.H. Freeman and Co., c1981
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Cold Spring Harbor Laboratory, NY: Cold Spring Harbor Laboratory Press, c2000
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Tudge, Colin
The impact of the gene : from Mendel's peas to designer babies
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In the name of eugenics: genetics and the uses of human heredity
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Kitcher P.
The lives to come : the genetic revolution and human possibilities
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Phage and the Origins of Molecular Biology.
Cold Spring Harbor: Cold Spring Harbor Laboratory Press., 1992.
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Chadarevian, Soraya de
Designs for life: molecular biology after World War II
New York: Cambridge University Press, 2002
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(Annals of the New York Academy of Sciences ; v. 758)
New York, N.Y.: New York Academy of Sciences, 1995
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Kay, Lily E.
The molecular vision of life: Caltech, the Rockefeller Foundation, and the rise of the new biology
New York : Oxford University Press, 1993
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Cambridge, Mass.:Harvard University Press, c2000
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Cambridge, Mass. : Harvard University Press, 1998
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Olby, Robert C.; foreword by Francis Crick
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London: Macmillan, 1974
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Pauly, Philip J.
Biologists and the promise of American life: from Meriwether Lewis to Alfred Kinsey
Princeton, N.J. : Princeton University Press, C2000.
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Perutz, Max
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Cold Spring Harbor: Cold Spring Harbor Laboratory Press., 2002.
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Portugal, Franklin H.
A century of DNA: a history of the discovery of the structure and function of the genetic substance
Cambridge, Mass.: MIT Press, c1977
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Rabinow, Paul
Making PCR : a story of biotechnology
Chicago : University of Chicago Press, 1996
Polymerase chain reaction--History
Soifer, Valerii
Lysenko and the tragedy of Soviet science
New Brunswick, N.J. : Rutgers University Press, c1994
Lysenko, Trofim Denisovich
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Sturtevant, Alfred H.
A history of genetics
New York : Harper & Row, 1965
Genetics - History
Tudge, Colin
The impact of the gene : from Mendel's peas to designer babies
New York : Hill and Wang, 2001
Genetics -- History
Cook-Deegan, Robert M.
The gene wars : science, politics, and the human genome
New York : W.W. Norton & Co., 1994
Human Genome Project
Human gene mapping
Davies, Kevin
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New York: Free Press, c2001
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New York: J. Wiley, c1996
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Invisible frontiers: the race to synthesize a human gene
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New York : Times Books : Random House, c1995
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London ; New York : Bantam, c2002
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DNA: the secret of life
New York : Alfred A. Knopf, 2003
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Recombinant DNA : the untold story
New York : Crown Publishers, c1978
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The DNA story: a documentary history of gene cloning
San Francisco: W.H. Freeman and Co., c1981
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Chargaff, Erwin.
Essays on nucleic acids
New York: Elsevier, 1963
Nucleic acids
A Slot Machine A Broken Test Tube An Autobiography Analysis
Chargaff, Erwin.
The nucleic acids : chemistry and biology
New York, Academic Press, 1955
Nucleic acids
Jones, Walter
Nucleic acids: their chemical properties and physiological conduct
New York: Longmans, Green and Co., 1920
Nucleic acids
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A Slot Machine A Broken Test Tube An Autobiography Essay
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Nucleic acids
New York : The Chemical Catalog Company, 1931
Nucleic acids
Schrödinger, Erwin
What is life? The physical aspect of the living cell
Cambridge : Cambridge University Press, 1944
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A Slot Machine A Broken Test Tube An Autobiography Answer
Watson, James D. ... [et. al]
Recombinant DNA. 2nd ed.
New York : Scientific American Books : Distributed by W.H. Freeman, c1992
Recombinant DNA